College football Week 7 is here, bringing a packed Saturday with crucial conference clashes, playoff implications, and betting opportunities. From powerhouse showdowns to teams seeking redemption, this weekend’s lineup offers something for every bettor and fan.
Here’s a look at the best college football games to watch — complete with odds, key storylines, and expert betting insights. (All odds via DraftKings Sportsbook, as of Oct. 10. All times ET.)
No. 1 Ohio State @ No. 17 Illinois — Noon, FOX
Point spread: Ohio State -14
Moneyline: Ohio State -650 | Illinois +470
Total (O/U): 49.5
Betting outlook:
Ohio State enters 5–0, but many bettors are questioning how battle-tested they truly are. Their biggest win came against Texas in Week 1 — a team now outside the Top 25. Illinois, despite a 63–10 blowout loss to Indiana earlier in the season, has improved significantly on defense.
Prediction:
Expect Ohio State to dominate early with its passing game but struggle to cover a two-touchdown spread away from home.
Pick: Illinois +14
Best Bet: Under 49.5
No. 8 Alabama @ No. 14 Missouri — Noon, ABC
Point spread: Alabama -3
Moneyline: Alabama -162 | Missouri +136
Total (O/U): 51.5
Betting outlook:
Alabama is coming off a shaky first half against Vanderbilt but showed resilience to finish strong. Missouri, undefeated at 5–0, boasts one of the top defenses in college football — allowing under 17 points per game.
Prediction:
Expect a low-scoring battle. Missouri’s home-field edge and defense could make this closer than oddsmakers expect.
Pick: Missouri +3
Best Bet: Under 51.5
Also Read: Week 7 College Football 2025 Betting Picks: Missouri State, Middle Tennessee, Liberty vs. UTEP
No. 6 Oklahoma @ Texas — 3:30 p.m., ABC
Point spread: Texas -1.5
Moneyline: Texas -118 | Oklahoma -102
Total (O/U): 43.5
Betting outlook:
The Red River Rivalry is always unpredictable. Texas quarterback Arch Manning has faced scrutiny after an inconsistent few weeks, while Oklahoma’s QB situation remains uncertain due to John Mateer’s availability.
Prediction:
Both teams have strong defenses, and momentum could swing either way. Expect a grind-it-out affair with points at a premium.
Pick: Oklahoma +1.5
Best Bet: Under 43.5
Florida @ Texas A&M — 7 p.m., ESPN
Point spread: Texas A&M -7.5
Moneyline: Texas A&M -278 | Florida +225
Total (O/U): 46.5
Betting outlook:
Florida stunned Texas last week as an underdog and finds itself in that position again against unbeaten Texas A&M. The Aggies’ narrow 41–40 win over Notre Dame showed both firepower and defensive vulnerabilities.
Prediction:
The Gators’ offense is unpredictable, but their confidence after an upset win could keep this close.
Pick: Florida +7.5
Best Bet: Over 46.5
No. 10 Georgia @ Auburn — 7:30 p.m., ABC
Point spread: Georgia -3.5
Moneyline: Georgia -175 | Auburn +145
Total (O/U): 45.5
Betting outlook:
Georgia bounced back from a home loss to Alabama with a decisive win over Kentucky. Auburn, now 3–2, returns home after two consecutive defeats and will rely on its defense to slow the Bulldogs.
Prediction:
Georgia’s offense should be steady enough to edge Auburn, but the Tigers’ defense and crowd could make this tight.
Pick: Georgia ML (-175)
Best Bet: Under 45.5
Betting Summary
| Matchup | Spread Pick | Total Pick | Confidence |
|---|---|---|---|
| Ohio State @ Illinois | Illinois +14 | Under 49.5 | ⭐⭐⭐ |
| Alabama @ Missouri | Missouri +3 | Under 51.5 | ⭐⭐⭐⭐ |
| Oklahoma @ Texas | Oklahoma +1.5 | Under 43.5 | ⭐⭐⭐ |
| Florida @ Texas A&M | Florida +7.5 | Over 46.5 | ⭐⭐ |
| Georgia @ Auburn | Georgia ML | Under 45.5 | ⭐⭐⭐⭐ |
Week 7 offers bettors a chance to back underdogs and low totals. With key matchups across the SEC and Big Ten, sharp bettors may find more value in unders and close spreads rather than blowouts. Keep an eye on weather, injuries, and line movement before placing your wagers.
FAQs
Q1. What are the best college football games to watch this weekend?
The top Week 7 matchups include Ohio State vs Illinois, Alabama vs Missouri, Oklahoma vs Texas, Florida vs Texas A&M, and Georgia vs Auburn.
Q2. Which game has the tightest betting line this week?
Oklahoma vs Texas is nearly a pick’em, with Texas favored by just 1.5 points.
Q3. What’s the best betting trend for Week 7?
Underdogs have covered in 62% of Top 25 matchups this season, making this a good week to back teams like Missouri or Illinois.
Q4. How can I watch these games live?
Games will air across FOX, ABC, and ESPN. Check local listings for specific coverage times.
Q5. Is it legal to bet on college football?
Yes, wagering on college football is legal in most U.S. states with regulated sportsbooks like DraftKings, FanDuel, and BetMGM. Always bet responsibly.
