College football action heats up this week as Week 7 kicks off with two midweek matchups on Wednesday, Oct. 8. Betting fans have plenty to consider, from conference battles to potential parlays with strong payouts. The Missouri State Bears (2-3) host the Middle Tennessee Blue Raiders (1-4) at 7:30 p.m. ET in a Conference USA showdown. Meanwhile, Liberty (1-4) travels to face UTEP (1-4) in another key matchup that could shape betting strategies heading into the weekend.
Here’s a detailed look at the top Week 7 college football betting picks and predictions
Missouri State vs. Middle Tennessee (+2.5)
Missouri State and Middle Tennessee both aim to bounce back after losses in their previous games. The Bears’ defense is struggling, giving up 31.6 points and 403.2 total yards per game. That spells opportunity for Middle Tennessee, whose offense has averaged 16.4 points per contest.
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Senior quarterback Nicholas Vattiato has thrown for 1,125 yards with six touchdowns this season and has topped 240 passing yards in each of the last three games. Missouri State is 0-1 against the spread in conference play, and SportsLine’s model predicts the Blue Raiders will cover the 2.5-point spread in 58% of simulations.
Liberty (-1.5) vs. UTEP
Liberty and UTEP meet for the third time in history, with the Flames holding a 2-0 record in previous encounters. Liberty has dominated both matchups with wins of 14 points or more. UTEP enters this contest 0-1 against the spread in conference games and 1-2 after a loss.
Liberty is predicted to cover the spread in 68% of simulations, making them one of the top Week 7 college football picks. Expect a competitive game, but Liberty’s recent form and historical edge give bettors confidence in the Flames’ narrow favourite status.
Over 46.5 Points in Liberty vs. UTEP
The Over/Under is set at 46.5 points, some model projects a combined score of 52 points. UTEP is averaging 20.8 points per game with 346 total yards of offense. Sophomore QB Malachi Nelson has thrown for 1,142 yards, eight touchdowns, and nine interceptions this season, including two games with three passing TDs.
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Liberty junior QB Ethan Vaski has added 763 passing yards, six passing touchdowns, and two rushing scores. With both offenses capable of explosive plays, the Over hits in 68% of simulations.
Parlay Opportunity: +595 Payout
Betting fans looking to maximize returns can combine the model’s three picks—Middle Tennessee covering, Liberty covering, and the Over in Liberty vs. UTEP—into a parlay. A $100 wager on this combo would return $595 at Caesars Sportsbook.
Key Betting Odds for Wednesday, Oct. 8 (Subject to Change)
- Missouri State vs. Middle Tennessee: Middle Tennessee +2.5
- Liberty vs. UTEP: Liberty -1.5
- Liberty vs. UTEP: Over 46.5 points
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FAQs
Q: Which team is the safest pick for Week 7?
A: According to SportsLine, Liberty has the highest probability (68%) of covering the spread.
Q: Is the Over in Liberty vs. UTEP a good bet?
A: Yes, the model predicts a combined score of 52 points, hitting the Over 68% of the time.
Q: Can I make a profitable parlay with these picks?
A: Yes, combining the three picks into a parlay yields a potential +595 payout
